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Article

DNA Methylation in Depression and Depressive-Like Phenotype: Biomarker or Target of Pharmacological Intervention?

Current neuropharmacology - 15 Nov 2022

Paoli Caterina, Misztak Paulina, Mazzini Giulia, Musazzi Laura

Abstract excerpt

Major depressive disorder (MDD) is a debilitating psychiatric disorder, the third leading global cause of disability. Regarding aetiopathogenetic mechanisms involved in the onset of depressive disorders, the interaction between genetic vulnerability traits and environmental factors is believed to play a major role. Although much is still to be elucidated about the mechanisms through which the environment can...

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Identifiers

PMID: 35105292
DOI: 10.2174/1570159X20666220201084536
PMCID: PMC9890294

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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