Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Investigating the Relationship Between DNA Methylation, Genetic Variation, and Suicide Attempt in Bipolar Disorder.

Archives of suicide research : official journal of the International Academy for Suicide Research - 1 Jan 2026

Alrfooh Aysheh, Casten Lucas G, Gringer Richards Jenny, Wemmie John A, Magnotta Vincent A, Fiedorowicz Jess G, Michaelson Jacob, Williams Aislinn J, Gaine Marie E

Abstract excerpt

OBJECTIVE: Individuals with bipolar disorder are at increased risk for suicide, and this can be influenced by a range of biological, clinical, and environmental risk factors. Biological components associated with suicide include DNA modifications that lead to changes in gene expression. Common genetic variation and DNA methylation changes are some of the most frequent types of DNA findings associated with an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Calcium Channels, L-Type

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Genetic Predisposition to Disease

Share to Genetic Variation

Share to Risk Factors

Share to Suicidal Ideation

Share to Suicide, Attempted

Source

Open in PubMed Open full text

Identifiers

PMID: 40476679
DOI: 10.1080/13811118.2025.2511264
PMCID: PMC12309415

Genes

CACNA1C
IMPA2
INPP1
MIF
SIRT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Investigating the Relationship Between DNA Methylation, Genetic Variation, and Suicide Attempt in Bipolar Disorder.PMID 40476679Read ↗

Investigating the relationship between DNA methylation, genetic variation, and suicide attempt in bipolar disorderSemantic proximity Read ↗

Multivariate genome-wide association study of suicidal behaviors in >1.7 million individuals of diverse population descentsSemantic proximity Read ↗

Genome-Wide DNA Methylation Patterns in Suicide Victims: Identification of New Candidate Genes.Semantic proximity Read ↗

Genetics of suicide attempts in individuals with and without mental disorders: a population-based genome-wide association studySemantic proximity Read ↗

Genome-wide association study meta-analysis of suicide attempt identifies twelve genome-wide significant loci and implicates genetic risks for specific health factorsSemantic proximity Read ↗

Genetic contributions to suicidal thoughts and behaviors.Semantic proximity Read ↗

Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorderSemantic proximity Read ↗

Blood epigenome-wide association studies of suicide attempt in adults with bipolar disorderSemantic proximity Read ↗

SNP-associated differential methylation in ARHGEF38: insights into genetic-epigenetic interactions.Semantic proximity Read ↗

GWAS Meta-Analysis of Suicide Attempt: Identification of 12 Genome-Wide Significant Loci and Implication of Genetic Risks for Specific Health Factors.Semantic proximity Read ↗

Increased DNA methylation in the suicide brainSemantic proximity Read ↗

Genome-wide DNA methylation meta-analysis in the brains of suicide completersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.