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Article

Association between DNA Methylation Levels in Brain Tissue and Late-Life Depression in Community-Based Participants

2020-04-24

Abstract excerpt

<h4>Objective</h4> Major depressive disorder (MDD) arises from a combination of genetic and environmental risk factors and DNA methylation is one of the molecular mechanisms through which these factors can manifest. However, little is known about the epigenetic signature of MDD in brain tissue. This study aimed to investigate associations between brain tissue-based DNA methylation and late-life MDD. <h4>Methods</h...

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Literature Corpus work
59326728-fe3a-5797-a92c-515021faf2e3
DOI
10.1101/2020.04.21.20074021
Open publication

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Association between DNA Methylation Levels in Brain Tissue and Late-Life Depression in Community-Based ParticipantsDOI 10.1101/2020.04.21.20074021
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