Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mir155 regulates osteogenesis and bone mass phenotype via targeting S1pr1 gene

4 Jan 2023

Abstract excerpt

MicroRNA-155 (miR155) is overexpressed in various inflammatory diseases and cancer, in which bone resorption and osteolysis are frequently observed. However, the role of miR155 on osteogenesis and bone mass phenotype is still unknown. Here, we report a low bone mass phenotype in the long bone of Mir155 -Tg mice compared with wild-type mice. In contrast, Mir155 -KO mice showed a high bone mass phenotype and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Metabolism and Diseases
Share to Cytokine Signaling Pathways and Interactions
Share to FOXO transcription factor regulation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 36598122
DOI: 10.7554/elife.77742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mir155 regulates osteogenesis and bone mass phenotype via targeting S1pr1 genePMID 36598122Read ↗

MicroRNA-155 regulates osteogenesis and bone mass phenotype via targeting S1PR1 geneSemantic proximity Read ↗

The regulatory effect of miR-181c-5p on the differentiation function of bone marrow mesenchymal stem cells in postmenopausal osteoporotic miceSemantic proximity Read ↗

Osteoclast signaling-targeting miR-146a-3p and miR-155-5p are downregulated in Paget's disease of boneSemantic proximity Read ↗

miR-324 mediates bone homeostasis through the regulation of osteoblast and osteoclast differentiation and activitySemantic proximity Read ↗

miR-324 mediates bone homeostasis through the regulation of osteoblast and osteoclast differentiation and activitySemantic proximity Read ↗

The high-bone-mass phenotype of novel transgenic mice with LRP5 A241T mutation.Semantic proximity Read ↗

Reduced femoral bone mass in both diet-induced and genetic hyperlipidemia mice.Semantic proximity Read ↗

MicroRNA-27a is essential for bone remodeling by modulating p62-mediated osteoclast signalingSemantic proximity Read ↗

A NOTCH1/LSD1/BMP2 Co-Regulatory Network Mediated by miR-137 Negatively Regulates Osteogenesis of Human Adipose-Derived Stem CellsSemantic proximity Read ↗

The WNT1G177C mutation specifically affects skeletal integrity in a mouse model of osteogenesis imperfecta type XVSemantic proximity Read ↗

MicroRNA-155 facilitates skeletal muscle regeneration by balancing pro- and anti-inflammatory macrophages.Semantic proximity Read ↗

The LRP5 high-bone-mass mutation causes alveolar bone accrual with minor craniofacial alteration.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.