Article

miR-324 mediates bone homeostasis through the regulation of osteoblast and osteoclast differentiation and activity

2023-07-10

Abstract excerpt

microRNAs (miRNAs) are non-coding RNAs which modulate the expression of other RNA molecules. One miRNA can target many transcripts, allowing each miRNA to play key roles in many biological pathways. miR-324 is a miRNA previously implicated in bone and cartilage maintenance, defects of which result in common age-related diseases, such as osteoporosis or osteoarthritis (OA). In global miR-324-null mice cartilage dam...

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Literature Corpus work: 7c6eed3e-76fd-565c-be46-9db709520ccb
DOI: 10.1101/2023.07.10.548366

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