Article

MicroRNA-27a is essential for bone remodeling by modulating p62-mediated osteoclast signaling

2022-06-17

Abstract excerpt

The ability to simultaneously modulate a set of genes for lineage-specific development has made microRNA an ideal master regulator for organogenesis. However, most microRNA deletions do not exhibit obvious phenotypic defects possibly due to functional redundancy. MicroRNAs are known to regulate skeletal lineages as the loss of their maturation enzyme Dicer impairs bone remodeling processes. Therefore, it is import...

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Literature Corpus work: 499bf1c6-555a-5ab7-ae30-02bf80a523f6
DOI: 10.1101/2022.06.13.495939

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