Article
MicroRNA-155 facilitates skeletal muscle regeneration by balancing pro- and anti-inflammatory macrophages.
Cell death & disease - 9 Jun 2016
Nie M, Liu J, Yang Q, Seok H Y, Hu X, Deng Z-L, Wang D-Z
Abstract excerpt
Skeletal muscle has remarkable regeneration capacity and regenerates in response to injury. Muscle regeneration largely relies on muscle stem cells called satellite cells. Satellite cells normally remain quiescent, but in response to injury or exercise they become activated and proliferate, migrate, differentiate, and fuse to form multinucleate myofibers. Interestingly, the inflammatory process following injury...
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