Ovarian cancer onset across different BRCA mutation types: a view to a more tailored approach for BRCA mutated patients.

doi:10.1136/ijgc-2022-003893

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Article

Ovarian cancer onset across different BRCA mutation types: a view to a more tailored approach for BRCA mutated patients.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 6 Feb 2023

Marchetti Claudia, Ataseven Beyhan, Cassani Chiara, Sassu Carolina Maria, Congedo Luigi, D'Indinosante Marco, Cappuccio Serena, Rhiem Kerstin, Hahnen Eric, Lucci Cordisco Emanuela, Arbustini Eloisa, Harter Philipp, Minucci Angelo, Scambia Giovanni, Fagotti Anna

Abstract excerpt

OBJECTIVE: To evaluate the role of different specific types of germline breast cancer susceptibility BRCA mutations on the age of onset of high grade serous ovarian cancer. METHODS: This was a multicenter, international, retrospective cohort of 474 patients diagnosed with recurrent or newly diagnosed high grade serous ovarian cancer, with known germline mutations in BRCA1/2 genes, treated between January 2011 and...

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PMID: 36581488
DOI: 10.1136/ijgc-2022-003893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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