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Article

Early-Onset Ovarian Cancer <30 Years: What Do We Know about Its Genetic Predisposition?

International journal of molecular sciences - 30 Nov 2023

Horackova Klara, Janatova Marketa, Kleiblova Petra, Kleibl Zdenek, Soukupova Jana

Abstract excerpt

Ovarian cancer (OC) is one of the leading causes of cancer-related deaths in women. Most patients are diagnosed with advanced epithelial OC in their late 60s, and early-onset adult OC diagnosed ≤30 years is rare, accounting for less than 5% of all OC cases. The most significant risk factor for OC development are germline pathogenic/likely pathogenic variants (GPVs) in OC predisposition genes (including BRCA1,...

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Source

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Identifiers

PMID: 38069345
DOI: 10.3390/ijms242317020
PMCID: PMC10707471

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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