Article
No Association of Early-Onset Breast or Ovarian Cancer with Early-Onset Cancer in Relatives in BRCA1 or BRCA2 Mutation Families.
Genes - 20 Jul 2021
Imbert-Bouteille Marion, Corsini Carole, Picot Marie-Christine, Mizrahy Lucas, Akouete Sandrine, Huguet Helena, Thomas Frédéric, Geneviève David, Taourel Patrice, Ychou Marc, Galibert Virginie, Rideau Chloé, Baudry Karen, Kogut Kubiak Tatiana, Coupier Isabelle, Hobeika Rémy, Macary Yvette, Toledano Alain, Solassol Jérôme, Maalouf Antoine, Daures Jean-Pierre, Pujol Pascal
Abstract excerpt
According to clinical guidelines, the occurrence of very early-onset breast cancer (VEO-BC) (diagnosed ≤ age 30 years) or VEO ovarian cancer (VEO-OC) (diagnosed ≤ age 40 years) in families with BRCA1 or BRCA2 mutation (BRCAm) prompts advancing the age of risk-reducing strategies in relatives. This study aimed to assess the relation between the occurrence of VEO-BC or VEO-OC in families with BRCAm and age at BC or...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.