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Article

Somatic mutations in breast and serous ovarian cancer young patients: a systematic review and meta-analysis.

Revista da Associacao Medica Brasileira (1992) - 1 Jan 2000

Encinas Giselly, Maistro Simone, Pasini Fátima Solange, Katayama Maria Lucia Hirata, Brentani Maria Mitzi, Bock Geertruida Hendrika de, Folgueira Maria Aparecida Azevedo Koike

Abstract excerpt

OBJECTIVE: our aim was to evaluate whether somatic mutations in five genes were associated with an early age at presentation of breast cancer (BC) or serous ovarian cancer (SOC). METHODS: COSMIC database was searched for the five most frequent somatic mutations in BC and SOC. A systematic review of PubMed was performed. Young age for BC and SOC patients was set at ≤ 35 and ≤ 40 years, respectively. Age groups...

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Identifiers

PMID: 26603012
DOI: 10.1590/1806-9282.61.05.474

Genes

PTEN
CDH1
GATA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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