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Article

Differences in age at diagnosis of ovarian cancer for each BRCA mutation type in Japan: optimal timing to carry out risk-reducing salpingo-oophorectomy.

Journal of gynecologic oncology - 1 Jul 2022

Sekine Masayuki, Enomoto Takayuki, Arai Masami, Den Hiroki, Nomura Hiroyuki, Ikeuchi Takeshi, Nakamura Seigo

Abstract excerpt

OBJECTIVE: BRCA1 and BRCA2 mutation carriers are recommended to undergo risk-reducing salpingo-oophorectomy (RRSO) by age 40 and 45, respectively. However, the carriers have a different way of thinking about their life plan. We aimed to investigate the distribution of age at diagnosis of ovarian cancer (OC) patients to examine the optimal timing of RRSO in the carriers. METHODS: We examined a correlation between...

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Identifiers

PMID: 35557031
DOI: 10.3802/jgo.2022.33.e46
PMCID: PMC9250856

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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