Article
Impact of BRCA Mutation Status on Tumor Dissemination Pattern, Surgical Outcome and Patient Survival in Primary and Recurrent High-Grade Serous Ovarian Cancer: A Multicenter Retrospective Study by the Ovarian Cancer Therapy-Innovative Models Prolong Survival (OCTIPS) Consortium.
Annals of surgical oncology - 1 Jan 2023
Glajzer Jacek, Castillo-Tong Dan Cacsire, Richter Rolf, Vergote Ignace, Kulbe Hagen, Vanderstichele Adriaan, Ruscito Ilary, Trillsch Fabian, Mustea Alexander, Kreuzinger Caroline, Gourley Charlie, Gabra Hani, Taube Eliane T, Dorigo Oliver, Horst David, Keunecke Carlotta, Baum Joanna, Angelotti Timothy, Sehouli Jalid, Braicu Elena Ioana
Abstract excerpt
BACKGROUND: This study seeks to evaluate the impact of breast cancer (BRCA) gene status on tumor dissemination pattern, surgical outcome and survival in a multicenter cohort of paired primary ovarian cancer (pOC) and recurrent ovarian cancer (rOC). PATIENTS AND METHODS: Medical records and follow-up data from 190 patients were gathered retrospectively. All patients had surgery at pOC and at least one further rOC...
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