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Neanderthal introgression reintroduced functional alleles lost in the human out of Africa bottleneck

2019-01-29

Abstract excerpt

<h4>ABSTRACT</h4> Neanderthal ancestry remains across modern Eurasian genomes, and introgressed sequences influence diverse phenotypes, including immune, skin, and neuropsychiatric diseases. Interpretation of introgressed sequences has focused on alleles derived in the Neanderthal lineage. Here, we demonstrate that Neanderthal introgression also reintroduced thousands of ancestral hominin alleles lost in the Eura...

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Literature Corpus work
f8a9232f-9e3a-5bd2-8b95-b9939159abaa
DOI
10.1101/533257
Open publication

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Neanderthal introgression reintroduced functional alleles lost in the human out of Africa bottleneckDOI 10.1101/533257
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