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Article

Leveraging Multi-Ancestry Polygenic Risk Scores for Body Mass Index to Predict Antiretroviral Therapy-Induced Weight Gain.

Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing - 1 Jan 2023

Keat Karl, Hui Daniel, Xiao Brenda, Bradford Yuki, Cindi Zinhle, Daar Eric S, Gulick Roy, Riddler Sharon A, Sinxadi Phumla, Haas David W, Ritchie Marylyn D

Abstract excerpt

Widespread availability of antiretroviral therapies (ART) for HIV-1 have generated considerable interest in understanding the pharmacogenomics of ART. In some individuals, ART has been associated with excessive weight gain, which disproportionately affects women of African ancestry. The underlying biology of ART-associated weight gain is poorly understood, but some genetic markers which modify weight gain risk...

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PMID: 36540980
PMCID: PMC10091400

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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