Article
Trans-ethnic analysis of metabochip data identifies two new loci associated with BMI.
International journal of obesity (2005) - 1 Mar 2018
Gong J, Nishimura K K, Fernandez-Rhodes L, Haessler J, Bien S, Graff M, Lim U, Lu Y, Gross M, Fornage M, Yoneyama S, Isasi C R, Buzkova P, Daviglus M, Lin D-Y, Tao R, Goodloe R, Bush W S, Farber-Eger E, Boston J, Dilks H H, Ehret G, Gu C C, Lewis C E, Nguyen K-D H, Cooper R, Leppert M, Irvin M R, Bottinger E P, Wilkens L R, Haiman C A, Park L, Monroe K R, Cheng I, Stram D O, Carlson C S, Jackson R, Kuller L, Houston D, Kooperberg C, Buyske S, Hindorff L A, Crawford D C, Loos R J F, Le Marchand L, Matise T C, North K E, Peters U
Abstract excerpt
OBJECTIVE: Body mass index (BMI) is commonly used to assess obesity, which is associated with numerous diseases and negative health outcomes. BMI has been shown to be a heritable, polygenic trait, with close to 100 loci previously identified and replicated in multiple populations. We aim to replicate known BMI loci and identify novel associations in a trans-ethnic study population. SUBJECTS: Using eligible...
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