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Article

Soluble factors from TLR4- or TCR-activated cells contribute to stability of the resting phenotype and increase the expression of CXCR4 of human memory CD4 T cells.

Immunologic research - 1 Jun 2023

Ruelas-Galindo Isabel, Huerta Leonor

Abstract excerpt

It has been proposed that cytokines can induce activation of resting T cells in an antigen-independent manner. However, experimental conditions have included the use of fetal serum and nanogram concentrations of added cytokines. To evaluate the effect of cytokines and chemokines generated by activated immune cells on the phenotypic profile of human memory CD4 T cells, the cells were cultured in FBS-free...

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Source

Identifiers

PMID: 36539634
DOI: 10.1007/s12026-022-09345-1

Genes

TLR4
CD4
CXCR4
CCR5
CD2
CD28

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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