Article

IL-6 is a Key Factor in the Formation of Gut Tissue Resident Memory T Cells from Naïve T cells

2025-06-27

Abstract excerpt

Tissue resident memory CD4 + T cells (T RM s) populate mucosal sites and play a critical role in local immune responses. Gut T RM cells persist for extended periods in the gut mucosa where they rapidly respond to invading pathogens and provide long lasting protection. This study investigates the factors that mediate differentiation of naïve CD4 + T cells into cells presenting a gut T RM phenotype. Naïve CD4...

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Literature Corpus work: 4c0de13c-aef4-57c1-a7ae-89dd936c58c2
DOI: 10.1101/2025.06.23.660664

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