Article
Functional and phenotypic analysis of human memory CD8+ T cells expressing CXCR3.
Journal of leukocyte biology - 1 Aug 2006
Kobayashi Naoki, Kondo Takaaki, Takata Hiroshi, Yokota Shumpei, Takiguchi Masafumi
Abstract excerpt
Several chemokine receptors play an important role in the migration of naïve, memory, and effector T cells. Flow cytometric analyses showed that human CD8+ T cells with naïve (CD27+ CD28+ CD45RA+) or memory (CD27+ CD28+/- CD45RA+) phenotypes included a population expressing a high level of CXC chemokine receptor 3 (CXCR3high) and one expressing a low level of it (CXCR3low), but those with the effector phenotype...
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