Article
Umbilical cord-mesenchymal stem cells induce a memory phenotype in CD4+ T cells.
Frontiers in immunology - 1 Jan 2023
Sengun Ezgi, Wolfs Tim G A M, van Bruggen Valéry L E, van Cranenbroek Bram, Simonetti Elles R, Ophelders Daan, de Jonge Marien I, Joosten Irma, van der Molen Renate G
Abstract excerpt
Inflammation is a physiological state where immune cells evoke a response against detrimental insults. Finding a safe and effective treatment for inflammation associated diseases has been a challenge. In this regard, human mesenchymal stem cells (hMSC), exert immunomodulatory effects and have regenerative capacity making it a promising therapeutic option for resolution of acute and chronic inflammation. T cells...
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