Article
Peripheral human CD4+CD8+ T lymphocytes exhibit a memory phenotype and enhanced responses to IL-2, IL-7 and IL-15.
Scientific reports - 14 Sept 2017
Clénet Marie-Laure, Gagnon François, Moratalla Ana Carmena, Viel Emilie C, Arbour Nathalie
Abstract excerpt
CD4+CD8+ T lymphocytes account for 1-2% of circulating human T lymphocytes, but their frequency is augmented in several diseases. The phenotypic and functional properties of these T lymphocytes are still ill-defined. We performed an ex vivo characterization of CD4+CD8+ T lymphocytes from the blood of healthy individuals. We observed that CD4+CD8+ T lymphocytes exhibit several characteristics associated with...
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