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Article

Tumor cells-derived conditioned medium induced pro-tumoral phenotypes in macrophages through calcium-nuclear factor κB interaction.

BMC cancer - 19 Dec 2022

Zhang Yuexin, Zhang Ziqi, Chen Lei, Zhang Xiuyue

Abstract excerpt

BACKGROUND: The malignant behaviors of lung cancers are affected by not only cancer cells but also many kinds of stromal cells in tumor microenvironment (TME), including macrophages. Macrophages have been proven to extensively influence tumor progression through several mechanisms, among which switching of macrophages from pro-inflammatory phenotypes (M1-like) to anti-inflammatory phenotypes (M2-like) mediated by...

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Identifiers

PMID: 36536301
DOI: 10.1186/s12885-022-10431-8
PMCID: PMC9762082

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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