Article

NF-κB: Governing Innate Immunity in Cancer

2024-01-18

Abstract excerpt

Tumor-associated macrophages (TAMs) are the major component of the tumor microenvironment (TME), where they sustain tumour progression and anti-tumor immunity. Due to their plasticity, macrophages can exhibit anti- or pro-tumor functions through the expression of different gene sets leading to distinct macrophages phenotypes: M1-like or pro-inflammatory and M2-like or anti-inflammatory. NF-κB transcription factors...

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Literature Corpus work: a3089c39-0ff9-5bda-99d6-7882a63a1b19
DOI: 10.20944/preprints202401.1401.v1

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