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Article

NF-κB: Governing Macrophages in Cancer.

Genes - 31 Jan 2024

Cornice Jessica, Verzella Daniela, Arboretto Paola, Vecchiotti Davide, Capece Daria, Zazzeroni Francesca, Franzoso Guido

Abstract excerpt

Tumor-associated macrophages (TAMs) are the major component of the tumor microenvironment (TME), where they sustain tumor progression and or-tumor immunity. Due to their plasticity, macrophages can exhibit anti- or pro-tumor functions through the expression of different gene sets leading to distinct macrophage phenotypes: M1-like or pro-inflammatory and M2-like or anti-inflammatory. NF-κB transcription factors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38397187
DOI: 10.3390/genes15020197
PMCID: PMC10888451

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