Article
Staphylococcus aureus extracellular adherence protein (Eap) reduces immune cell phenotype in developing but not in established atherosclerotic lesions.
Biochimica et biophysica acta. Molecular basis of disease - 1 Mar 2023
Salzmann Manuel, Platzer Harald, Mussbacher Marion, Derler Martina, Lenz Max, Haider Patrick, Brekalo Mira, Kral-Pointner Julia B, Kastl Stefan, Speidl Walter S, Preissner Klaus T, Schubert Uwe, Bischoff Markus, Uhrin Pavel, Wojta Johann, Hohensinner Philipp J
Abstract excerpt
Atherosclerosis is a chronic, inflammatory disease of the vessel wall where triggered immune cells bind to inflamed endothelium, extravasate and sustain local inflammation. Leukocyte adhesion and extravasation are mediated by adhesion molecules expressed by activated endothelial cells, like intercellular adhesion molecule 1 (ICAM-1). Extracellular adherence protein (Eap) from Staphylococcus aureus binds to a...
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