Article
Apolipoprotein B 100 is a suppressor of S taphylococcus aureus‐induced innate immune responses in humans and mice
19 Jul 2012
Abstract excerpt
Plasma lipoproteins such as LDL (low-density lipoprotein) are important therapeutic targets as they play a crucial role in macrophage biology and metabolic disorders. The impact of lipoprotein profiles on host defense pathways against Gram-positive bacteria is poorly understood. In this report, we discovered that human serum lipoproteins bind to lipoteichoic acid (LTA) from Staphylococcus aureus and thereby alter...
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