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Article

SAP deficiency mitigated atherosclerotic lesions in ApoE(-/-) mice.

Atherosclerosis - 1 Jan 2016

Zheng Lingyun, Wu Teng, Zeng Cuiling, Li Xiangli, Li Xiaoqiang, Wen Dingwen, Ji Tianxing, Lan Tian, Xing Liying, Li Jiangchao, He Xiaodong, Wang Lijing

Abstract excerpt

OBJECTIVE: Serum amyloid P conpoent (SAP), a member of the pentraxin family, interact with pathogens and cell debris to promote their removal by macrophages and neutrophils and is co-localized with atherosclerotic plaques in patients. However, the exact mechanism of SAP in atherogenesis is still unclear. We investigated whether SAP influence macrophage recruitment and foam cell formation and ultimately affect...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26649902
DOI: 10.1016/j.atherosclerosis.2015.11.009

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