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Article

Extracellular adherence protein of Staphylococcus aureus suppresses disease by inhibiting T-cell recruitment in a mouse model of psoriasis.

The Journal of investigative dermatology - 1 Mar 2010

Wang Honglin, von Rohrscheidt Julia, Roehrbein Jan, Peters Thorsten, Sindrilaru Anca, Kess Daniel, Preissner Klaus T, Scharffetter-Kochanek Karin

Abstract excerpt

Psoriasis is a T-cell-mediated inflammatory disease. Previous studies focused on lymphocyte function-associated antigen 1 (LFA-1)-expressing T cells as a molecular target for therapeutic intervention. By contrast, information on therapeutic effects and the underlying mechanism of blocking the LFA-1 counter receptor, ICAM-1 is scarce. Here, we used the CD18 (beta2-integrin) hypomorphic (CD18hypo) mouse model of...

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Identifiers

PMID: 19812597
DOI: 10.1038/jid.2009.310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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