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Article

Genetic Variation of SAMM50 Is Not an Independent Risk Factor for Alcoholic Hepatocellular Carcinoma in Caucasian Patients.

International journal of molecular sciences - 5 Dec 2022

Nischalke Hans Dieter, Schmalz Franziska, Buch Stephan, Fischer Janett, Möller Christine, Matz-Soja Madlen, Krämer Benjamin, Langhans Bettina, Klüners Alexandra, Soyka Michael, Stickel Felix, Nattermann Jacob, Berg Thomas, Strassburg Christian P, Lutz Philipp

Abstract excerpt

Hepatocellular carcinoma (HCC) is a severe complication of advanced alcoholic liver disease, which is modulated by genetic predisposition. Identifying new genetic loci might improve screening. Genetic variation of SAMM50 was linked to HCC. We aimed to validate this finding in a large cohort of patients with advanced alcoholic liver disease (ALD). A large, well-characterised cohort of patients with alcoholic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Liver Cirrhosis, Alcoholic

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Source

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Identifiers

PMID: 36499681
DOI: 10.3390/ijms232315353
PMCID: PMC9740343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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