Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.

doi:10.1053/j.gastro.2020.06.014

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.

Gastroenterology - 1 Oct 2020

Innes Hamish, Buch Stephan, Hutchinson Sharon, Guha Indra Neil, Morling Joanne R, Barnes Eleanor, Irving Will, Forrest Ewan, Pedergnana Vincent, Goldberg David, Aspinall Esther, Barclay Stephan, Hayes Peter C, Dillon John, Nischalke Hans Dieter, Lutz Philipp, Spengler Ulrich, Fischer Janett, Berg Thomas, Brosch Mario, Eyer Florian, Datz Christian, Mueller Sebastian, Peccerella Teresa, Deltenre Pierre, Marot Astrid, Soyka Michael, McQuillin Andrew, Morgan Marsha Y, Hampe Jochen, Stickel Felix

Abstract excerpt

BACKGROUND AND AIMS: Little is known about genetic factors that affect development of alcohol-related cirrhosis. We performed a genome-wide association study (GWAS) of samples from the United Kingdom Biobank (UKB) to identify polymorphisms associated with risk of alcohol-related liver disease. METHODS: We performed a GWAS of 35,839 participants in the UKB with high intake of alcohol against markers of hepatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Europe

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Heterogeneous-Nuclear Ribonucleoproteins

Share to Liver Cirrhosis, Alcoholic

Share to Mitochondrial Proteins

Share to Nuclear Proteins

Share to Oxidoreductases

Share to Risk Assessment

Source

Open in PubMed

Identifiers

PMID: 32561361
DOI: 10.1053/j.gastro.2020.06.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-Wide Association Study for Alcohol-Related Cirrhosis Identifies Risk Loci in MARC1 and HNRNPUL1.PMID 32561361Read ↗

Genome-wide Association Study and Meta-analysis on Alcohol-Associated Liver Cirrhosis Identifies Genetic Risk Factors.Semantic proximity Read ↗

Genetic variants that associate with cirrhosis have pleiotropic effects on human traits.Semantic proximity Read ↗

A polygenic risk score for alcohol-associated cirrhosis among heavy drinkers with European ancestry.Semantic proximity Read ↗

Genetic Variants in Liver Cirrhosis: A Review of Classification, Mechanisms, and Clinical Relevance CirrhosisSemantic proximity Read ↗

A genetic risk score and diabetes predict development of alcohol-related cirrhosis in drinkers.Semantic proximity Read ↗

Association of Genetic Variation With Cirrhosis: A Multi-Trait Genome-Wide Association and Gene-Environment Interaction Study.Semantic proximity Read ↗

Genome-Wide Association Studies in Hepatocellular Carcinoma: Aetiology-Specific Susceptibility, Functional Interpretation, and Clinical Translation.Semantic proximity Read ↗

Associations of Alcohol Consumption and Genetic Predisposition to Hepatic Steatosis With Liver-Related Events: Results From Large Population-Based Cohort Studies.Semantic proximity Read ↗

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis.Semantic proximity Read ↗

A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.Semantic proximity Read ↗

Molecular Alterations Caused by Alcohol Consumption: A Mendelian Randomisation StudySemantic proximity Read ↗

Molecular Alterations Caused by Alcohol Consumption in the UK Biobank: A Mendelian Randomisation Study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.