Article
Liposome-based nanoparticles impact on regulatory and effector phenotypes of macrophages and T cells in multiple Sclerosis patients.
Biomaterials - 1 Jan 2023
Tredicine Maria, Ria Francesco, Poerio Noemi, Lucchini Matteo, Bianco Assunta, De Santis Federica, Valentini Mariagrazia, De Arcangelis Valeria, Rende Mario, Stabile Anna Maria, Pistilli Alessandra, Camponeschi Chiara, Nociti Viviana, Mirabella Massimiliano, Fraziano Maurizio, Di Sante Gabriele
Abstract excerpt
Current available treatments of Multiple Sclerosis (MS) reduce neuroinflammation acting on different targets on the immune system, but potentially lead to severe side effects and have a limited efficacy in slowing the progression of the disease. Here, we evaluated in vitro the immunomodulatory potential of a new class of nanoparticles - liposomes, constituted by a double-layer of phosphatidylserine (PSCho/PS),...
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