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Article

Teriflunomide attenuates neuroinflammation-related neural damage in mice carrying human PLP1 mutations.

Journal of neuroinflammation - 3 Jul 2018

Groh Janos, Hörner Michaela, Martini Rudolf

Abstract excerpt

BACKGROUND: Genetically caused neurological disorders of the central nervous system (CNS) are mostly characterized by poor or even fatal clinical outcome and few or no causative treatments are available. Often, these disorders are associated with low-grade, disease-promoting inflammation, another feature shared by progressive forms of multiple sclerosis (PMS). We previously generated two mouse lines carrying...

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Identifiers

PMID: 29970109
DOI: 10.1186/s12974-018-1228-z
PMCID: PMC6031103

Genes

PLP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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