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Article

The effect of haptoglobin genotype on the association of asymmetric dimethylarginine and DDAH 1 polymorphism with diabetic macroangiopathy.

Cardiovascular diabetology - 2 Dec 2022

Wang Shiyun, Deng Zixuan, Zhang Hong, Zhang Rong, Yan Dandan, Zheng Xiaojiao, Jia Weiping, Hu Cheng

Abstract excerpt

BACKGROUND: Dimethylarginine dimethylaminohydrolase (DDAH) 1 maintains the bioavailability of nitric oxide by degrading asymmetric dimethylarginine (ADMA). Here, we aimed to investigate the effect of haptoglobin (Hp) genotype on the association of ADMA and DDAH 1 polymorphism with diabetic macroangiopathy. METHODS: In stage 1, 90 Chinese participants with type 2 diabetes were enrolled to measure a panel of...

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Identifiers

PMID: 36461077
DOI: 10.1186/s12933-022-01702-6
PMCID: PMC9716717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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