Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study.

Cardiovascular diabetology - 9 Feb 2011

Lu Tse-Min, Lin Shing-Jong, Lin Ming-Wei, Hsu Chiao-Po, Chung Ming-Yi

Abstract excerpt

BACKGROUND: Elevated plasma levels of asymmetric dimethylarginine (ADMA) has been reported to be associated with insulin resistance and micro/macrovascular diabetic complications, and may predict cardiovascular events in type 2 diabetic patients. Dimethylarginine dimethylaminohydrolase 1 (DDAH1) is the major enzyme eliminating ADMA in humans, but the effect of genetic variations in DDAH1 on type 2 diabetes and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amidohydrolases
Share to Arginine
Share to Blood Glucose

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromatography, High Pressure Liquid

Share to Coronary Angiography

Share to Linear Models

Share to Proportional Hazards Models

Share to Taiwan

Source

Open in PubMed Open full text

Identifiers

PMID: 21303562
DOI: 10.1186/1475-2840-10-16
PMCID: PMC3050685

Genes

DDAH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The association of dimethylarginine dimethylaminohydrolase 1 gene polymorphism with type 2 diabetes: a cohort study.PMID 21303562Read ↗

Sequence variation in DDAH1 and DDAH2 genes is strongly and additively associated with serum ADMA concentrations in individuals with type 2 diabetes.Semantic proximity Read ↗

Relationship between DDAH gene variants and serum ADMA level in individuals with type 1 diabetes.Semantic proximity Read ↗

Genetic and environmental determinants of dimethylarginines and association with cardiovascular disease in patients with type 2 diabetes.Semantic proximity Read ↗

A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with insulin sensitivity.Semantic proximity Read ↗

DDAH1 promoter -396 4N insertion variant is associated with increased risk of type 2 diabetes in a gender-dependent manner.Semantic proximity Read ↗

Association of the DDAH2 gene polymorphism with type 2 diabetes and hypertension.Semantic proximity Read ↗

The effect of haptoglobin genotype on the association of asymmetric dimethylarginine and DDAH 1 polymorphism with diabetic macroangiopathy.Semantic proximity Read ↗

Genome-wide association study of L-arginine and dimethylarginines reveals novel metabolic pathway for symmetric dimethylarginine.Semantic proximity Read ↗

Association Between ALDH2 Polymorphisms and the Risk of Diabetes Mellitus in Hypertensive PatientsSemantic proximity Read ↗

Relationship between dimethylarginine dimethylaminohydrolase gene variants and asymmetric dimethylarginine in patients with rheumatoid arthritis.Semantic proximity Read ↗

Association of CYP19A1 and CYP1A2 genetic polymorphisms with type 2 diabetes mellitus risk in the Chinese Han population.Semantic proximity Read ↗

A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with chronic kidney disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.