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Article

The MTHFR C677T/A1298C polymorphism is associated with increased risk of microangiopathy in type 2 diabetes mellitus: A systematic review and meta-analysis.

Nutrition research (New York, N.Y.) - 1 Oct 2024

Zhang Yuxin, Zhang Yanjiao, Miao Runyu, Fang Xinyi, Yin Ruiyang, Guan Huifang, Tian Jiaxing

Abstract excerpt

Extensive case-control association studies have been conducted over the past few decades to investigate the relationship between MTHFR polymorphism and type 2 diabetes mellitus (T2DM) microangiopathy. However, the strength of the evidence and clinical significance are unclear. Consequently, a meta-analysis was performed to examine the correlations between two prevalent MTHFR single nucleotide polymorphisms, MTHFR...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 39340999
DOI: 10.1016/j.nutres.2024.08.004

Genes

MTHFR
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Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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The MTHFR C677T/A1298C polymorphism is associated with increased risk of microangiopathy in type 2 diabetes mellitus: A systematic review and meta-analysis.PMID 39340999Read ↗

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