Article
Interaction between haptoglobin genotype and glycemic variability on diabetic macroangiopathy: a population-based cross-sectional study.
Endocrine - 1 Nov 2023
Deng Zixuan, Wang Shiyun, Lu Jingyi, Zhang Rong, Zhang Lei, Lu Wei, Zhu Wei, Bao Yuqian, Zhou Jian, Hu Cheng
Abstract excerpt
PURPOSE: Haptoglobin (Hp) is a hemoglobin-binding protein that functions as an antioxidant in human plasma. It is reported that glycemic variability (GV) plays a key role in diabetes-related complications associated with impaired glucose metabolism and oxidative stress. Here we aim to investigate whether the effect of GV on diabetic macroangiopathy depends on Hp genotype in type 2 diabetes. METHODS: A number of...
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