Article
In-depth investigation of the point mutation pattern of HIV-1.
Frontiers in cellular and infection microbiology - 1 Jan 2022
Sun Nan, Yau Stephen S-T
Abstract excerpt
Mutations may produce highly transmissible and damaging HIV variants, which increase the genetic diversity, and pose a challenge to develop vaccines. Therefore, it is of great significance to understand how mutations drive the virulence of HIV. Based on the 11897 reliable genomes of HIV-1 retrieved from HIV sequence Database, we analyze the 12 types of point mutation (A>C, A>G, A>T, C>A, C>G, C>T, G>A, G>C, G>T,...
Topics
- HIV-1
- Point Mutation
- Mutation
- Mutation, Missense
- Databases, Nucleic Acid