Article
[Sequence variation of HIV and bioinformatics].
Uirusu - 1 Jun 2004
Yamaguchi-Kabata Yumi
Abstract excerpt
The envelope glycoprotein of human immunodeficiency virus type 1 (HIV-1) interacts with receptors on the target cell and mediates virus entry by fusing the viral and cell membranes. To maintain the viral infectivity, amino acids that interact with receptors are expected to be more conserved than the other sites on the protein surface. In contrast to the functional constraint of amino acids for the receptor...
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