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Point mutation bias in SARS-CoV-2 variants results in increased ability to stimulate inflammatory responses

20 Oct 2020

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection induces severe pneumonia and is the cause of a worldwide pandemic. Coronaviruses, including SARS-CoV-2, have RNA proofreading enzymes in their genomes, resulting in fewer gene mutations than other RNA viruses. Nevertheless, variants of SARS-CoV-2 exist and may induce different symptoms; however, the factors and the impacts of these mutations...

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PMID: 33082451
DOI: 10.1038/s41598-020-74843-x

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