Article
Identification of NRAS Diagnostic Biomarkers and Drug Targets for Endometrial Cancer-An Integrated in Silico Approach.
International journal of molecular sciences - 18 Nov 2022
Alessandro Larsen, Low Kat-Jun Eric, Abushelaibi Aisha, Lim Swee-Hua Erin, Cheng Wan-Hee, Chang Sook-Keng, Lai Kok-Song, Sum Yap Wai, Maran Sathiya
Abstract excerpt
The diagnosis of endometrial cancer involves sequential, invasive tests to assess the thickness of the endometrium by a transvaginal ultrasound scan. In 6−33% of cases, endometrial biopsy results in inadequate tissue for a conclusive pathological diagnosis and 6% of postmenopausal women with non-diagnostic specimens are later discovered to have severe endometrial lesions. Thus, identifying diagnostic biomarkers...
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