Article
Mutation status coupled with RNA-sequencing data can efficiently identify important non-significantly mutated genes serving as diagnostic biomarkers of endometrial cancer.
BMC bioinformatics - 28 Dec 2017
Liu Keqin, He Li, Liu Zhichao, Xu Junmei, Liu Yuan, Kuang Qifan, Wen Zhining, Li Menglong
Abstract excerpt
BACKGROUND: Endometrial cancers (ECs) are one of the most common types of malignant tumor in females. Substantial efforts had been made to identify significantly mutated genes (SMGs) in ECs and use them as biomarkers for the classification of histological subtypes and the prediction of clinical outcomes. However, the impact of non-significantly mutated genes (non-SMGs), which may also play important roles in the...
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