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Article

Genetic variation and the mitogen-activated protein kinase (MAPK) signaling pathway.

Omics : a journal of integrative biology - 1 Jan 2006

Cho Stewart, Savas Sevtap, Ozcelik Hilmi

Abstract excerpt

Non-synonymous single nucleotide polymorphisms (nsSNPs) are known to alter protein function, contributing to disease susceptibility. This report explores the nature of nsSNPs in the gene products of the highly conserved mitogen-activated protein kinase (MAPK) signaling pathways already implicated in cancer development. MAPK signaling pathways regulate cellular processes such as proliferation, differentiation,...

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Source

Identifiers

PMID: 16584319
DOI: 10.1089/omi.2006.10.66

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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