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Article

Polygenic Risk Scores for Atherosclerotic Cardiovascular Disease in the Asia-Pacific Region

1 Dec 2021

Abstract excerpt

Approximately one-half of the phenotypic susceptibility to atherosclerotic cardiovascular disease (ASCVD) has a genetic basis. Although individual allelic variants generally impart a small effect on risk for ASCVD, an emerging body of data has shown that the aggregation and weighting of many of these genetic variations into "scores" can further discriminate an individual's risk beyond traditional risk factors...

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PMID: 36341217
DOI: 10.1016/j.jacasi.2021.08.008

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