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Article

The evolution of genetic-based risk scores for lipids and cardiovascular disease

30 Jan 2019

Abstract excerpt

PURPOSE OF REVIEW: With improved next-generation sequencing technology, open-access genetic databases and increased awareness of complex trait genetics, we are entering a new era of risk assessment in which genetic-based risk scores (GRSs) will play a clinical role. We review the concepts underlying polygenic models of disease susceptibility and challenges in clinical implementation. RECENT FINDINGS: Polygenic...

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Share to Diabetes, Cardiovascular Risks, and Lipoproteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30676533
DOI: 10.1097/mol.0000000000000576

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