Article
Data-Driven Chronic Allograft Phenotypes: A Novel and Validated Complement for Histologic Assessment of Kidney Transplant Biopsies.
Journal of the American Society of Nephrology : JASN - 1 Nov 2022
Vaulet Thibaut, Divard Gillian, Thaunat Olivier, Koshy Priyanka, Lerut Evelyne, Senev Aleksandar, Aubert Olivier, Van Loon Elisabet, Callemeyn Jasper, Emonds Marie-Paule, Van Craenenbroeck Amaryllis, De Vusser Katrien, Sprangers Ben, Rabeyrin Maud, Dubois Valérie, Kuypers Dirk, De Vos Maarten, Loupy Alexandre, De Moor Bart, Naesens Maarten
Abstract excerpt
BACKGROUND: No validated system currently exists to realistically characterize the chronic pathology of kidney transplants that represents the dynamic disease process and spectrum of disease severity. We sought to develop and validate a tool to describe chronicity and severity of renal allograft disease and integrate it with the evaluation of disease activity. METHODS: The training cohort included 3549 kidney...
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