Article
Data-driven Derivation and Validation of Novel Phenotypes for Acute Kidney Transplant Rejection using Semi-supervised Clustering.
Journal of the American Society of Nephrology : JASN - 3 May 2021
Vaulet Thibaut, Divard Gillian, Thaunat Olivier, Lerut Evelyne, Senev Aleksandar, Aubert Olivier, Van Loon Elisabet, Callemeyn Jasper, Emonds Marie-Paule, Van Craenenbroeck Amaryllis, De Vusser Katrien, Sprangers Ben, Rabeyrin Maud, Dubois Valérie, Kuypers Dirk, De Vos Maarten, Loupy Alexandre, De Moor Bart, Naesens Maarten
Abstract excerpt
BACKGROUND: Over the past decades, an international group of experts iteratively developed a consensus classification of kidney transplant rejection phenotypes, known as the Banff classification. Data-driven clustering of kidney transplant histologic data could simplify the complex and discretionary rules of the Banff classification, while improving the association with graft failure. METHODS: The data consisted...
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