Article

Precision Sub-phenotyping of Histologically Stable Kidney Transplants by a Composite Molecular and Cellular Instability Score

2019-12-19

Abstract excerpt

Acute Rejection (AR) is the main cause of the graft dysfunction and premature graft loss, and diagnosis of rejection before advanced histological injury is crucial to salvage graft function. However, recent molecular studies have highlighted the unrecognized burden of sub-clinical graft rejection when graft function is preserved, and a dichotomy exists, of a histologically normal biopsy with molecular signatures o...

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Literature Corpus work: e43f3ca7-f80c-5eb5-b698-59503476c1cd
DOI: 10.1101/2019.12.18.881706

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