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Continuous Transcriptomic Indices for Assessing the Spectrum of Kidney Transplant Rejection: International Derivation and Validation Study

2026-03-12

Abstract excerpt

<title>Abstract</title> <p>Kidney allograft rejection is currently defined by categorical Banff histologic thresholds, despite reflecting a continuous spectrum of immune injury. Here we developed four continuous molecular indices capturing rejection severity and injury stage: antibody-mediated microvascular injury (AMR/MVI), T cell–mediated tubulointerstitial inflammation (TCMR/TI), inflammatory activity and chro...

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Literature Corpus work
dac022e2-1abd-588b-8d24-00ed931b2317
DOI
10.21203/rs.3.rs-9012525/v1
Open publication

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Continuous Transcriptomic Indices for Assessing the Spectrum of Kidney Transplant Rejection: International Derivation and Validation StudyDOI 10.21203/rs.3.rs-9012525/v1
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