Article
An integrated view of molecular changes, histopathology and outcomes in kidney transplants.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Oct 2010
Halloran P F, de Freitas D G, Einecke G, Famulski K S, Hidalgo L G, MengeL M, Reeve J, Sellares J, Sis B
Abstract excerpt
Data-driven approaches to deteriorating kidney transplants, incorporating histologic, molecular and HLA antibody findings, have created a new understanding of transplant pathology and why transplants fail. Transplant dysfunction is best understood in terms of three elements: diseases, the active injury-repair response and the cumulative burden of injury. Progression to failure is mainly attributable to...
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