Back to search

Article

Continuous indices to assess the phenotypic spectrum of kidney transplant rejection

2024-12-10

Abstract excerpt

The international Banff classification for kidney transplant pathology discretizes the rejection continuum into distinct diagnostic categories, introducing artificial dichotomization and threshold effects. To better reflect the underlying disease spectrum, we developed, in this cohort study, two novel indices for quantifying antibody-mediated (AMR) and T-cell mediated rejection (TCMR) from histological lesion scor...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
88dda165-a8c8-5ea5-ab2c-3daad5057451
DOI
10.1101/2024.12.10.24318058
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Continuous indices to assess the phenotypic spectrum of kidney transplant rejectionDOI 10.1101/2024.12.10.24318058
Continuous Transcriptomic Indices for Assessing the Spectrum of Kidney Transplant Rejection: International Derivation and Validation StudySemantic proximity
The Banff 2024 Kidney Meeting Report: Rejection as a spectrum of phenotypes and focus on differential diagnostic reasoning.Semantic proximity
Clinical and Histological Phenotypes of Antibody-Mediated Rejection in Kidney Transplant: A Single-Center Experience from Latin America.Semantic proximity
Probable antibody-mediated rejection in kidney transplantation is a rare and challenging phenotype to define: Findings from a single-center study.Semantic proximity
Antibody-mediated rejection, T cell-mediated rejection, and the injury-repair response: new insights from the Genome Canada studies of kidney transplant biopsies.Semantic proximity
Data-Driven Chronic Allograft Phenotypes: A Novel and Validated Complement for Histologic Assessment of Kidney Transplant Biopsies.Semantic proximity
Molecular Analysis of Renal Allograft Biopsies: Where Do We Stand and Where Are We Going?Semantic proximity
Development and Validation of a Multiclass Model Defining Molecular Archetypes of Kidney Transplant Rejection: A Large Cohort Study of the Banff Human Organ Transplant Gene Expression PanelSemantic proximity
Machine learning-supported interpretation of kidney graft elementary lesions in combination with clinical dataSemantic proximity
Potential and Uncertainties of RejectClass in Acute Kidney Graft Dysfunction: An Independent Validation Study.Semantic proximity
Precision Sub-phenotyping of Histologically Stable Kidney Transplants by a Composite Molecular and Cellular Instability ScoreSemantic proximity
The Molecular Phenotype of Kidney Transplants: Insights From the MMDx Project.Semantic proximity
Select a neighboring publication to make it the new centre.